This course focuses on computational methods for studying protein and RNA structure, protein-protein interactions, and biological networks. Algorithms for prediction of RNA secondary structure, protein-protein interactions, and annotation of protein secondary/tertiary structure and function are studied in depth. Students will apply various computer programs and structure-visualization software to secondary and tertiary protein structure prediction, structure-structure comparison, protein domain classification, annotation of functionally important sites, and protein design. Interesting aspects of protein interaction and metabolic networks are also discussed.

Course prerequisite(s): 

605.205 Molecular Biology for Computer Scientists or equivalent. 605.651 Principles of Bioinformatics is recommended.

Course instructor(s): 

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