This course introduces statistical methods that are widely used in modern applications. A balance is struck between the presentation of the mathematical foundations of concepts in probability and statistics and their appropriate use in a variety of practical contexts. Foundational topics of probability, such as probability rules, related inequalities, random variables, probability distributions, moments, and jointly distributed random variables, are followed by foundations of statistical inference, including estimation approaches and properties, hypothesis testing, and model building. Data analysis ranging from descriptive statistics to the implementation of common procedures for estimation, hypothesis testing, and model building is the focus after the foundational methodology has been covered. Software, for example R-Studio, will be leveraged to illustrate concepts through simulation and to serve as a platform for data analysis.