Dr. Eric Pohlmeyer

Applied Biomedical Engineering

Personal Bio

Dr. Eric Pohlmeyer received the B.S. degree in mechanical engineering from the University of Cincinnati, Cincinnati, and the M.S. and Ph.D. degrees in Biomedical engineering from Northwestern University, Evanston, IL.  Currently, Dr. Pohlmeyer is a senior researcher in the Research & Exploratory Development Department of the Johns Hopkins University Applied Physics Laboratory, as part of the Intelligent Systems Group.  When he is not writing about himself in the third person, Dr. Pohlmeyer does research in neural decoding, motor function and brain-machine/brain-computer interfaces.  He has developed brain-machine interfaces (BMIs) that are capable of controlling robotic arms using reinforcement learning algorithms as well as BMIs that can decode desired hand movements from the brain and translate them into electrical stimulation of what would otherwise be paralyzed muscles in order to restore wrist function in nonhuman primates.  He has also worked with EEG-based neural interfaces in humans, in particular with cortically coupled computer vision (C3Vision) systems that incorporate EEG recordings with computer vision systems in order to help individuals sort through large-scale image databases to find specific images, as well as systems that can monitor cognitive workload and assess task difficulty and familiarity of information to a person.

Education History

  • BS Mechanical Engineering, University of Cincinnati
  • MS Biomedical Engineering, Northwestern University
  • PhD Biomedical Engineering, Northwestern University

Work Experience

Senior Professional Staff, JHU Applied Physics Laboratory

Publications

Journal Articles
--"Using reinforcement learning to provide stable brain-machine interface control despite neural input reorganization"
Pohlmeyer EA, Mahmoudi B, Geng S, Prins NW and Sanchez JC,
PLoS ONE 9(1): e87253, 2014.
--“Closing the loop in cortically-coupled computer vision: a brain-computer interface for searching image databases”
Pohlmeyer EA, Wang J, Jangraw DC, Lou B, Chang SF, and Sajda P,
Journal of Neural Engineering, 8(3):036025, 2011.
--“Towards autonomous neuroprosthetic control using Hebbian reinforcement learning”
Mahmoudi B, Pohlmeyer EA, Prins NW, Geng S, Sanchez JC
Journal of Neural Engineering, 10(6):066005, 2013.
-- “The Effects of Targeted Muscle Reinnervation on Neuromas in a Rabbit Rectus Abdominis Flap Model”
Kim PS, Ko JH, O'Shaughnessy KK, Kuiken TA, Pohlmeyer EA, and Dumanian GA
Journal of Hand Surgery, 2012.
--“In a blink of an eye and a switch of a transistor: Cortically coupled computer vision”
Sajda P, Pohlmeyer EA, Wang J, Parra LC, Christoforou C, Dmochowski J, Hanna B, Bahlmann C, Singh MK, and Chang, S (invited paper)
Proceedings of the IEEE, 98(3): 462-478, 2010.
--“Toward the restoration of hand use to a paralyzed monkey: brain-controlled functional electrical stimulation of forearm muscles”
Pohlmeyer EA, Oby ER, Perreault EJ, Solla SA, Kilgore KL, Kirsch RF, and Miller LE
PLoS One, 4(6): e5924, 2009.
--“A fully implanted drug delivery system for peripheral nerve blocks in behaving animals”
Pohlmeyer EA, Jordon LR, Kim P, and Miller LE
Journal of Neuroscience Methods, 182(2): 165-171, 2009.
--“Prediction of upper limb muscle activity from motor cortical discharge during reaching”
Pohlmeyer EA, Solla SA, Perreault EJ, and Miller LE
Journal of Neural Engineering, 4(4): 369-379, 2007.
--“Biomimetic Brain Machine Interfaces for the Control of Movement”
Fagg AH, Hatsopoulos NG, Lafuente V, Moxon KA, Nemati S, Rebesco JM, Romo R, Solla SA, Reimer J, Tkach D, Pohlmeyer EA, Miller LE
J. Neuroscience, (27): 11824-11846, 2007
--“Identification of multiple-input systems with highly coupled inputs: application to EMG prediction from multiple intracortical electrodes”
Westwick DT, Pohlmeyer EA, Solla SA, Miller LE, and Perreault EJ
Neural Computation 18(2): 329-55, 2006.

Conference Proceedings
--“Representation of Natural Arm and Robotic Arm Movement in the Striatum of a Marmoset Engaged in a Two Choice Task”
Prins NW, Geng S, Pohlmeyer EA, Prasad A, Sanchez JC
IEEE/EMBS Conference on Neural Engineering (NER) (2013). San Diego, California, USA
--“Extraction of Error Related Local Field Potentials from the Striatum During Environmental Perturbations of a Robotic Arm”
Geng G, Prins NW, Pohlmeyer EA, Prasad A, Sanchez JC
IEEE/EMBS Conference on Neural Engineering (NER) (2013). San Diego, California, USA
-- “A new method of concurrently visualizing states, values, and actions in reinforcement based brain machine interfaces”
Bae J, Sanchez Giraldo LG, Pohlmeyer EA, Sanchez JC, Principe JC, in IEEE International Conference of the Engineering in Medicine and Biology Society, Osaka, Japan, 2013.
--“Feature extraction and unsupervised classification of neural population reward signals for reinforcement based BMI”
Prins NW, Geng S, Pohlmeyer EA, Mahmoudi B, Sanchez JC, in IEEE International Conference of the Engineering in Medicine and Biology Society, Osaka, Japan, 2013.
--“Brain-Machine Interface Control of a Robot Arm Using Actor-Critic Reinforcement Learning”
Pohlmeyer EA, Mahmoudi B, Geng S, Prins N and Sanchez JC, in IEEE International Conference of the Engineering in Medicine and Biology Society, San Diego, CA, 2012.
--“Decoding Tradeoffs in Multiscale Neuronal Recording for Brain-Machine Interfaces”
Prasad A, Pohlmeyer E, Mahmoudi B and Sanchez JC, in IEEE International Conference of the Engineering in Medicine and Biology Society, Boston, MA, 2011.
--“Combining Computer and Human Vision into a BCI: Can the whole be greater than the sum of its parts?”
Pohlmeyer EA, Jangraw DC, Wang J, Chang S-F, Sajda P
32nd International Conference of the IEEE Engineering in Medicine and Biology Society, 2010
--“Brain state decoding for rapid image retrieval”
Wang J, Pohlmeyer EA, Hanna B, Jiang Y, Sajda P, Chang S
17th ACM International Conference on Multimedia, 2009, pp 945-954
--“Use of Intracortical Recordings to Control a Hand Neuroprosthesis”
Pohlmeyer EA, Perreault EJ, Slutzky MW, Kilgore KL, Kirsch RF, Taylor DM, Miller LE
3rd International IEEE EMBS Conference on Neural Engineering, 2007, pp 418-420
--“Real-Time Control of the Hand by Intracortically Controlled Functional Neuromuscular Stimulation”
Pohlmeyer EA, Perreault EJ, Slutzky MW, Kilgore KL, Kirsch RF, Taylor DM, Miller LE
10th International Conference On Rehabilitation Robotics, 2007
--“Optimal Input Selection for MISO Systems Identification: Applications to BMIs”
Perreault EJ, Westwick DT, Pohlmeyer EA, Solla SA, Miller LE
2nd International IEEE EMBS Conference on Neural Engineering, 2005, pp 167-170
--“Prediction of EMG from Multiple Electrode Recordings in Primary Motor Cortex”
Pohlmeyer EA, Miller LE, Mussa-Ivaldi FA, Perreault EJ, Solla SA.
Annual mtg., IEEE Int. Conf. Eng. in Med. Biol. Soc., 2003, p. 2197-2200

Poster Abstracts
--“Deciding to take action: Striatum activation during reaching to targets of varying reward value”
E. A. Pohlmeyer, S. Geng, N W Prins, J.C.Sanchez
Society for Neuroscience (2013). San Diego, California, USA
--“Reinforcement learning as the basis for a brain-machine interface controller of a reaching robot arm”
E. A. Pohlmeyer, B. Mahmoudi, N Prins, S. Geng, J.C.Sanchez
Society for Neuroscience (2012). New Orleans, Louisiana, USA
--“Linking Motor and Reward: The Correlation between Nucleus Accumbens and Primary Motor Cortex during Goal Directed Reaching”
E. Pohlmeyer, B. Mahmoudi, S. Geng, N. Prins, and J. C. Sanchez
Neural Control of Movement 22nd Annual Meeting (2012), Venice, Italy
--“A primate model of cortically controlled FES for grasp”
E. A. Pohlmeyer, L. E. Miller, K. L. Kilgore, L. R. Jordan
Society for Neuroscience (2006). Atlanta, Georgia, USA
--“Prediction of EMG from multiple electrode recordings in M1”
E. A. Pohlmeyer, L. E. Miller, F. A. Mussa-Ivalidi, E. J. Perreault and S. A. Solla
Neural Control of Movement 13th Annual Meeting (2003). Santa Barbara, California, USA

Professional Organizations

Society for Neuroscience