Dr. Vassiliy Tsytsarev

Applied Biomedical Engineering

Education History

  • Ph.D Biology, Saint Petersburg State University

Work Experience

Assistant Research Professor, University of Maryland, College Park


1. Muller BJ, Zhdanov AV, Borisov SM, Foley T, Okkelman IA, Tsytsarev V, Tang Q, Erzurumlu RS, Chen Y, Zhang H, Toncelli C, Klimant I, Papkovsky DB, Dmitriev RI; Nanoparticle-Based Fluoroionophore for Analysis of Potassium Ion Dynamics in 3D Tissue Models and In Vivo; Adv. Funct. Mater. 2018, 1704598

2. Tsytsarev V, Arakawa H, Zhao S Chedotal A, Erzurumlu RS. Behavioral consequences of a bifacial map in the mouse somatosensory cortex, J Neurosci. 2017, 37(30):7209-7218

3. Lee LJ, Tsytsarev V, Erzurumlu RS Structural and functional differences in the barrel cortex of Mecp2 null mice. J Comp Neurol. 2017; 15;525(18):3951-3961

4. Kwon SE, Tsytsarev V, Erzurumlu RS, O'Connor DH. Organization of orientation- specific whisker deflection responses in layer 2/3 of mouse somatosensory cortex. Neuroscience. 2017 ; 4. pii: S0306-4522(17)30553-5

5. Tang Q, Liu Y, Tsytsarev V, Lin J, Wang B, Kanniyappan U, Li Z, Chen Y. High- dynamic-range fluorescence laminar optical tomography (HDR-FLOT). Biomed Opt Express. 2017; 8(4):2124-2137

6. Nag OK, Stewart MH, Deschamps JR, Susumu K, Oh E, Tsytsarev V, Tang Q, L Efros A, Vaxenburg R, Black BJ, Chen Y, O'Shaughnessy TJ, North SH, Field LD, Dawson PE, Pancrazio JJ, Medintz IL, Chen Y, Erzurumlu RS, Huston AL, Delehanty JB. Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of In Vitro and In Vivo Cellular Membrane Potential. ACS Nano. 2017 ; 27;11(6):5598-5613

7. Tsytsarev V, Akkenti F, Pumbo E, Tang Q, Chen Y, Erzurumlu RS, Papkovsky DB. Planar Implantable Sensor for In Vivo Measurement of Cellular Oxygen Metabolism in Brain Tissue. J Neurosci Methods. 2017; 20; 281:1-6

8. Nikzad S, Chen Y, Tsytsarev V, Kateb B, Grundfest W. Special Section Guest Editorial: Brain Mapping and Therapeutics. Neurophotonics. 2017;4(1):011001

9. Tang Q, Lin J, Tsytsarev V, Erzurumlu RS, Liu Y, Chena Y. Review of mesoscopic optical tomography for depth-resolved imaging of hemodynamic changes and neural activities, Neurophotonics 2017 4(1):011009

10. Gottschalk S, Fehm TF, Dean-Ben XL, Tsytsarev V, and Razansky D. Correlation Between Volumetric Oxygenation Responses and Electrophysiology Identifies Deep Thalamo-Cortical Activity During Epileptic Seizures; Neurophotonics, Neurophotonics. 2017; 4(1):011007

11. Tang Q, Tsytsarev V (Co-First author), Frank A, Wu Y, Chen CW, Erzurumlu RS, Chen Y. (2016) In Vivo Mesoscopic Voltage-Sensitive Dye Imaging of Brain Activation. Sci Rep. Nature Publishing Group, 29;6:25269

12. Tsytsarev V, Pumbo E, Tang Q, Chen C-W, Kalchenko V, Chen Y. (2016) Study of the cortical representation of whisker frequency selectivity using voltage-sensitive dye optical imaging. Intravital, VOL. 5, NO. 1, e1142637

13. Tang Q, Tsytsarev V (Co-First author), Liang C-P, Akkentli F, Erzurumlu RS, Chen
Y. (2015) In Vivo Voltage-Sensitive Dye Imaging of Subcortical Brain Function, Sci Rep. Nature Publishing Group 2015 27;5:17325.

14. Arakawa H, Suzuki A, Zhao S, Tsytsarev S, Lo F-S, Hayashi Y, Itohara S, Iwasato T, Erzurumlu RS. (2014) Thalamic NMDA receptor function is necessary for patterning of the thalamocortical somatosensory map and for sensorimotor behaviors. J Neurosci. 3;34(36):12001-14

15. Tsytsarev V, Liao L-D, Kong KV, Liu YH, Erzurumlu RS, Olivo M and Thakor NV. (2014) Recent Progress in Voltage-Sensitive Dye Imaging for Neuroscience J. Nanosci. Nanotechnol. 14, 4733-4744

16. Lo FS, Akkentli F, Tsytsarev V, Erzurumlu RS. (2013) Functional significance of cortical NMDA receptors in somatosensory information processing. J Neurophysiol.110(11):2627-36

17. Tsytsarev V, Rao B, Maslov KI, Li L, Wang LV. (2013) Photoacoustic and optical coherence tomography of epilepsy with high temporal and spatial resolution and dual optical contrasts. J Neurosci Methods. J Neurosci Methods. 15;216(2):142-5

18. Tsytsarev V, Arakawa H, Borisov S, Pumbo E, Erzurumlu RS, Papkovsky DB. (2013) In vivo imaging of brain metabolism activity using a phosphorescent oxygen- sensitive probe. J Neurosci Methods. J Neurosci Methods. 15;216(2):146-51

19. Liao LD, Tsytsarev V, Delgado-Martínez I, Li ML, Erzurumlu R, Vipin A, Orellana J, Lin YR, Lai HY, Chen YY, Thakor NV. (2013) Neurovascular coupling: in vivo optical techniques for functional brain imaging. Biomed Eng Online. 30;12(1):38

20. Tsytsarev V, Bernardelli C, Maslov KI. (2012) Living Brain Optical Imaging: Technology, Methods and Applications. J of Neuroscience and Neuroengineering; 1: 180-192

21. Lenkov DN, Volnova AB, Pope ARD, Tsytsarev V. (2012) Advantages and limitations of brain imaging methods in the research of absence epilepsy in humans and animal models. J Neurosci Methods. S0165-0270(12)00443-8

22. Yao J, Xia J, Maslov K, Nasiriavanaki M, Tsytsarev V, Demchenko AV, Wang LV; (2012) Noninvasive photoacoustic computed tomography of mouse brain metabolism in vivo; Neuroimage; 64C:257-266

23. Tsytsarev V, Maslov K, Yao J, Parameswar AR, Demchenko AV, Wang LV. (2012) In vivo imaging of epileptic neuronal activity using a fluorescent deoxyglucose analog (2-NBDG); J Neurosci Methods. 203(1):136-40

24. Tsytsarev V, Hu S, Yao J, Maslov K, Barbour DL, Wang LV (2011) Cortical Microvascular Responses to Direct Electrical Stimulation: an Optical-Resolution Photoacoustic Microscopy Study. J Biomedical Optics 16(7), 076002-6

25. Tsytsarev V, Pope D, Pumbo E, Yablonskii A, Hofmann M. (2010) Study of the cortical representation of whisker directional deflection using voltage-sensitive dye optical imaging. Neuroimage. Oct 15;53(1):233-8

26. Tsytsarev V, Pope D, Pumbo E, Garver W. (2010) Intrinsic Optical Imaging of Directional Selectivity in Rat Barrel Cortex: Application of the Multidirectional Magnetic Whiskers Stimulator; J Neurosci Methods 30;189 (1):80-3

27. Tsytsarev V, Yao J, Hu S, Li L, Favazza CP, Maslov KI, Wang LV (2010). Invasive and Transcranial Photoacoustic Imaging of the Vascular Response to Brain Electrical Stimulation. Proc. SPIE, Vol. 7564, 756407

28. Li L, Rao B, Tsytsarev V, Wang LV. (2010) Integrated photoacoustic and optical coherence microscopy and its biomedical applications. in Biomedical Optics, OSA Technical Digest, Optical Society of America, BWE3

29. Hu S, Maslov K, Tsytsarev V, Wang LV, (2009) Functional transcranial brain imaging by optical-resolution photoacoustic microscopy J. Biomed. Opt. 14 (4), 501-4

30. Tsytsarev V, Fukuyama H, Pope D, Pumbo E, Kimura M. (2009) Optical imaging of interaural time difference representation in rat auditory cortex; Frontiers in Neuroengineering; 2, 1-7

31. Tsytsarev V, Premachandra K, Takeshita D, Bahar S. (2008) Imaging cortical electrical stimulation in vivo: fast intrinsic optical signal versus voltage-sensitive dyes; Optics Letters, 33; 9, 1032-1034

32. Tsytsarev V, Taketani M, Schottler F,Tanaka S, Hara M. (2006) New planar multielectrode array: recording from a rat auditory cortex. J. Neural. Eng. 3, 293–298

33. Callan D, Tsytsarev V, Hanakawa T, Callan A, Katsuhara M, Fukuyama H, Turner R. (2006) NeuroImage. Song and Speech: Brain Regions Involved with Perception and Covert Production. 31, 1327-42

34. Tsytsarev V, Kirilkin I, Khiroug L. Transcranial in vivo optical imaging using confocal microscopy (2005). J Cogn Neurosci Suppl, 31-32

35. Tsytsarev V, Yamazaki T, Ribot, J, and Tanaka S. (2004). Sound frequency representation in cat auditory cortex. NeuroImage 23, 1246–1255.

36. Tsytsarev V, Tanaka S. (2003). Functional Mapping: Mapping Intrinsic Signals of the Auditory Cortex. The Journal of the Brain Science Institute of RIKEN, 10; 5

37. Tsytsarev V, Tanaka S. (2002). Intrinsic optical signals from rat primary auditory cortex in response to sound stimuli presented to contralateral, ipsilateral and bilateral ears. Neuroreport 13, 1661–1665

38. Tsytsarev V, Lenkov D, Volnova A. (1999) Effect of tetanization of the motor cortex on neuronal responses in the albino rat mesial cortex. Fiziol Zh Im I M Sechenova 85(8), 1116-8

39. Ignashchenkova A, Tsytsarev V, Lenkov D. (1998) Study of peripheral and central inputs into the mesial cortex in adult and developing rats. Eur J Neurosci Suppl 10 : 3132

40. Inyushin M, Tsytsarev V, Ignashchenkova A, Lenkov D. (1997) Use of artificial ion channels for quasi-intracellular recording of cerebral cortex neuron activity. Neurosci Behav Physiol 27:6 702-7

41. Tsytsarev V, Ignashchenkova A. (1996). Effect of stimulation of the peripheral pathways and somatosensory cortex on the neuronal activity of the medial wall of the prefrontal cortex in the white rat. Fiziol Zh Im I M Sechenova. 82:1, 45-51

42. Tsytsarev V, Golikova T. (1994) The influence of cingulate cortex stimulation on the activity of neurons of the motor cortex in the white rat. Neurosci Behav Physiol.24:5 438-9

43. Tsytsarev V, Golikova T. (1993) The effect of stimulation of the cingulate cortex on the neuronal activity of the motor cortex in the white rat. Fiziol Zh Im I M Sechenova. 79:9, 106-8

Professional Organizations

Society for Brain Mapping and Theraputics
Society for Neuroscience