Nanostructured materials intrinsically possess large surface area (interface area) to volume ratios. It is this large interface area that gives rise to many of the amazing properties and technologies associated with nanotechnology. In this class, we will examine how the properties of surfaces, interfaces, and nanoscale features differ from their macroscopic behavior. We will compare and contrast fluid-fluid interfaces with solid-fluid and solid-solid interfaces, discussing fundamental interfacial physics and chemistry, as well as touching on state-of-the-art technologies.