Computational Biomechanics and Physiological Modeling - 585.762

This course introduces the theory and application of computational methods for modeling systems of the human body, with an emphasis on multiscale musculoskeletal biomechanics, as well as the physiology surrounding the function of the human musculoskeletal system. Students will begin by developing foundational mathematical skills in MATLAB, using differential equations to model and predict physiological processes such as action potential propagation, the respiratory system, and bone remodeling. Building on this foundation, the course explores advanced computational approaches, including inverse kinematics, inverse dynamics, and computed muscle control for simulating human movement in OpenSim. Students will also learn nonlinear finite element analysis for modeling human tissue dynamics and predicting injury, as well as having an opportunity to dive into cutting-edge techniques from current scientific literature. By the end of the course, students will gain both theoretical understanding and practical skills in computational physiology and biomechanics, preparing them to tackle real-world problems with modeling and simulation.

Course Prerequisite(s)

An advanced math class, such as EN.585.615: Mathematical Methods or EN.535.641: Mathematical Methods for Engineers, is required.