The World Wide Web Consortium (W3C) is endeavoring to create standards and technology that support a distributed “Web of data.” Collectively, these advances allow the systems we develop to work and interact more effectively, through the use of XML-based languages, and information on how various tags relate to real-world objects and concepts. This course covers a range of Semantic Web technologies, including RDF (Resource Description Framework – a model for data interchange) and OWL (Web Ontology Language), as well as domain-specific standards and ontologies (formal specifications of how to represent objects and concepts). Representative applications of RDF, OWL, and ontologies to various problems will be discussed. Students will apply course concepts to an in-depth project in an area of personal or professional interest. Prerequisite(s): EN.605.202 Data Structures. Course Note(s): This course may be counted toward a three course track in Bioinformatics.