This course will focus on the design and development of science and payload operations centers, and their use to execute the science operations of space missions. Course topics will include science activity planning, interfaces with mission operations and ground systems, science data pipelines, archive delivery, data analysis and science decision making, and operation of the SOC during a mission. Students will learn about the needs of the science and instrument teams, as well as the broader science community, and how to design and operate a software system to satisfy their requirements. Examples will be presented from real missions, with assignments that illustrate the various topics building towards a final simulated science planning activity where the student will step into the shoes of an instrument operations lead and execute a plan using the tools and skills they have developed.Some programming experience in Python, Java, or similar strongly recommended.