This course focuses on the application of engineering fundamentals to designing biological tissue substitutes. Concepts of tissue development, structure and function will be introduced. Students will learn to recognize the majority of histological tissue structures in the body and understand the basic building blocks of the tissue and clinical need for replacement. The engineering components required to develop tissue-engineered grafts will be explored including biomechanics and transport phenomena along with the use of biomaterials and bioreactors to regulate the cellular microenvironment. Emphasis will be placed on different sources of stem cells and their applications to tissue engineering. Clinical and regulatory perspectives will be discussed.Prerequisite(s): Knowledge of basic molecular and cellular biology, physiology, and math through ordinary differential equations is required.
Course Prerequisite(s)
EN.585.601 Applied Physiology I, EN.585.602 Applied Physiology II and EN.585.607 Molecular Biology
Course Offerings
There are no sections currently offered, however you can view a sample syllabus from a prior section of this course.