Computational Methods in Biomedical Engineering - 585.762

This course will teach the theory and application of computational techniques for modeling the systems of the human body, with a significant focus on musculoskeletal biomechanics. We will begin with MATLAB examples using differential equations to explain, model, and predict biological phenomena including action potential propagation, viscoelasticity, bone remodeling, and other physiologic processes. Further discussion will center around advanced computational techniques including inverse kinematics, inverse dynamics, and computed muscle control for modeling macroscopic human movement in OpenSim; non-linear finite element analysis of human tissue in a commercial solver; and other cutting edge computational methods from the scientific literature. We aim to provide students with the theoretical foundation and applied skills to excel in the field of biological modeling and simulation.

Course Prerequisite(s)

A physiology course, such as EN.585.601: Physiology for Applied Biomedical Engineering I or EN.585.602: Physiology for Applied Biomedical Engineering II, is required. An advanced math class, such as EN.585.615: Mathematical Methods or EN.535.641: Mathematical Methods for Engineers, is also required.