Siddharth (Sidd) Shenoy, PhD is a Health Science Administrator in the Division of Lung Diseases at National Heart Lung Blood Institute. He served as a Scientific Program Analyst contractor from Columbus Technologies and Services that is supported SPARC Program, BRAIN and HEAL Initatives and Translational Neural Device efforts at NIH/NINDS. He graduated with a BS and PhD in Biomedical Engineering from the University of North Carolina-Chapel Hill. His PhD research in Dr. Brian Button’s lab at the Marsico Lung Institute revolved around a novel paradigm of testing air-flow velocities associated with breathing and cough using human lung epithelial cells in an ex vivo lung bioreactor model using hi-speed videography and particle tracking methodologies. Recently, as a postdoctoral fellow, he gained additional translational pre-clinical and clinical experience at the Wilmer Eye Institute at the Center for Nanomedicine at Johns Hopkins University under the guidance of Professor Justin Hanes and Dr. Jung Soo Suk. He investigated the relationship between microstructural (e.g. pore size) properties of mucus revealed by particle tracking non-mucoadhesive nanoparticles with key clinical pulmonary outcomes in patients with pulmonary exacerbations. With a background in electromechanical design, machining, microelectronics, electrophysiology and computer programming, he has mentored design teams across the globe in COVID19 design competitions hosted by Johns Hopkins University and Massachusetts Institutes of Technology. Utilizing these experiences, he will be teaching a course on Advanced Pulmonary Therapeutics at Engineering for Professionals Department in the Whiting School of Engineering, Johns Hopkins University.
- B.S. Applied Sciences: Biomedical Engineering, University of North Carolina – Chapel Hill
- Ph.D Biomedical Engineering, University of North Carolina – Chapel Hill
Leslie Morgan, Ana Jaramillo, Siddharth Shenoy, Dorota Raclawska, Nkechinyere Emezienna, Vanessa Richardson, Naoko Hara, Anna Harder, James NeeDell, Corinne Hennessy, Hassan El-Batal, Chelsea Magin, Dianne Grove Villalon, Gregg Duncan, Justin Hanes, Jung Suk, David Thornton, Fernando Holguin, William Janssen, William Thelin, and Christopher Evans. “Disulfide disruption reverses mucus dysfunction in allergic airway disease.” Nat Commun 12, 249 (2021). https://doi.org/10.1038/s41467-020-20499-0
Sachin S. Thakur and Siddharth Shenoy, Jung Soo Suk, Justin Hanes, Ehsan Vaghefi, Ilva Rupenthal. “Validation of hyaluronic acid-agar based gels as vitreous humour substitutes for in vitro drug delivery evaluations.” (European Journal of Pharmaceutics and Biopharmaceutics, Jan 2020). Mar; 148:118-125. doi: 10.1016/j.ejpb.2020.01.008.
Henry Goodell, Siddharth Shenoy, Nathan Shenkute, Elijah Lackey, Robert Dennis and Brian Button. “Adhesive and Cohesive Peel Force Measurement of Human Airway Mucus.” Bio-protocol 9(13): e3287. DOI: 10.21769/BioProtoc.3287 (July 2019).
Jane Chisholm, Siddharth Shenoy, Julie Shade, Victor Kim, Nirupama Putcha, Kathryn Carson, Robert Wise, Nadia Hansel, Justin Hanes, Jung Soo Suk and Enid Neptune. “Nanoparticle diffusion in spontaneously expectorated sputum as a biophysical tool to probe
disease severity in COPD.” (European Respiratory Journal, June 2019). PMID: 31164433
Karina Negron, Namir Khalasawi, Billy Lu, Jason Lee, Siddharth Shenoy, Tza-Huei Wang, Justin Hanes, and Jung Soo Suk. “Widespread Gene Transfer to Malignant Glioma with In viro-to-In vivo Correlation” (Journal of Controlled Release, Apr 2019). PMID: 309784314
Brian Button, Henry Goodell, Eyad Atieh, Chen Yu-Cheng, Robert Williams, Siddharth Shenoy, Elijah Lackey, Nathan Shenkute, Liheng Cai, Robert Dennis, Richard Boucher, and Michael Rubinstein. “Defective Cough Clearance in Muco-Obstructive Diseases: Mechanisms and Therapies.” (PNAS, Nov 2018). PMID: 30420506
Johns Hopkins Post Doctoral Association